What specific supplements should individuals consider incorporating into their regimen while undergoing treatment with Tirzepatide for obesity management? Given the complexity of metabolic responses and the unique pharmacodynamics associated with this glucagon-like peptide-1 (GLP-1) receptor agonist, are there particular micronutrients or dietary enhancements that might bolster its efficacy? Could certain vitamins or minerals, such as potassium or magnesium, play a crucial role in optimizing metabolic function or mitigating potential side effects? Furthermore, how might the incorporation of omega-3 fatty acids or probiotics impact gut health and overall well-being during this therapeutic approach? Is it advisable to consult with a healthcare professional to tailor a supplement strategy that aligns with individual health needs and lifestyle factors? What considerations should be taken into account regarding possible interactions between supplements and medications? In what ways can personalized nutritional guidance support the efficacy of Tirzepatide in achieving sustainable weight loss outcomes?