Should I take pre-workout supplements before hitting the pavement for a run? This question often pervades the minds of athletes and fitness enthusiasts alike, especially when considering the myriad of options available on the market today. With the intention of optimizing performance, enhancing endurance, and potentially elevating energy levels, many ponder if these products truly possess the transformative power they claim. What ingredients should one scrutinize in a pre-workout formula? Do stimulants like caffeine play a pivotal role, or might other components, such as beta-alanine or citrulline malate, be more advantageous for sustained cardio efforts? Furthermore, how do individual responses to these supplements vary based on factors such as body composition, hydration status, and even psychological preparedness? Additionally, can the consumption of pre-workout lead to any adverse effects during running, such as gastrointestinal discomfort or anxious jitters? Ultimately, is it feasible to determine a universal answer to this question, or does it hinge largely on personal experience and desired outcomes?