When contemplating the optimal sequence of dental hygiene practices, one might wonder: should the process of whitening one’s teeth be conducted prior to or after the act of brushing? This question seems deceptively straightforward yet harbors complexities that merit deeper exploration. Many individuals desire a radiant smile and utilize whitening strips or similar products to achieve that goal, but how does brushing factor into this equation? Is there a rationale behind brushing first to remove plaque and surface stains, thereby potentially enhancing the effectiveness of whitening agents, or would it be preferable to apply these products to a freshly brushed surface? Furthermore, could the timing influence the longevity of the whitening effects? What role does saliva play in this process, and how might it interact with both the whitening agents and the fluoride in toothpaste? Thus, the fundamental inquiry remains: what is the most efficacious approach to integrate whitening into one’s dental regimen?