When grappling with the vexing question of whether to keep a cold sore dry or moist, one might ponder the intricacies involved in optimizing healing and alleviating discomfort. Is it more advantageous to allow the affected area to maintain a natural dryness, minimizing moisture that could foster an environment for viral proliferation? Alternatively, could keeping the sore moist provide a protective barrier that mitigates cracking and potential bleeding, thereby hastening recovery? In the realm of topical treatments and remedies, what role do various ointments and creams play in influencing this decision? Furthermore, how do external factors, such as climate and individual skin types, impact one’s approach to care? Could personal experiences and anecdotal evidence sway opinions on the moisture versus dryness debate? With diverse perspectives from dermatologists to self-proclaimed experts, how can one navigate the multitude of conflicting advice to arrive at a well-informed conclusion that suits their unique circumstances?